After months of preparation and high-profile jury questioning, Sean “Diddy” Combs’ federal sex trafficking trial is officially underway in Manhattan. The music mogul and entrepreneur faces charges that could send him to prison for life. But even before opening statements, the prosecution is grappling with a major setback: the disappearance of a key witness.

Prosecution Loses Contact With Critical Witness In Diddy Case

Assistant U.S. Attorney Maurene Comey revealed in court that the government has lost communication with one of the alleged victims, identified only as Victim 3. The woman’s absence throws a wrench into the government’s plan, which relies heavily on her testimony to link Combs to some of the most serious allegations.

“The disappearance of a key victim at trial is crippling for the prosecution,” said defense attorney John J. Perlstein. “The government will have to adjust quickly, and we’ll see if their case can stand without her.”

Legal experts say the prosecution still has other witnesses, including staffers and former associates from Combs’ inner circle. But without all the alleged victims on the stand, the emotional punch of the case is weakened.

Punishing Allegations Paint Combs As Ringleader Of Criminal Enterprise

The 54-year-old Combs is charged with racketeering conspiracy, sex trafficking by force, fraud or coercion, and transportation to engage in prostitution. Prosecutors allege he ran a decades-long operation through his businesses — including Bad Boy Entertainment and Combs Global — where he coerced women into sexual acts with men he called “freaks” during drug-fueled parties he filmed for his own use.

According to the indictment, Combs lured women with promises of love and career advancement. When they resisted, he used threats, intimidation, and violence to force compliance. The so-called “freak off” parties became a key part of the government’s case.

Lead Witness Cassie Ventura To Testify Despite Past Abuse Video

Casandra “Cassie” Ventura, Combs’ former girlfriend and the government’s lead witness, is expected to take the stand under her real name. Ventura, who is currently pregnant with her third child, is identified in court documents as Victim 1. Her testimony is sure to be pivotal — and emotionally charged.

Ventura’s decade-long relationship with Combs ended in 2018. Prosecutors say she will detail the physical and emotional abuse she endured, including sexual coercion. This comes less than a year after Ventura and Combs settled a civil lawsuit filed by her — though the settlement was not an admission of wrongdoing.

Last year, a surveillance video leaked by CNN showed Combs violently assaulting Ventura in a hotel hallway. The footage sparked public outrage. Combs apologized, calling his behavior “inexcusable” and saying he sought therapy and rehab. The defense, however, plans to frame the altercation as part of a “mutually violent” relationship — a risky strategy that aims to separate the assault from the sex trafficking charges.

Diddy’s Defense Team Faces Tough Task Of Separating Abuse From Criminal Allegations

Defense attorneys are expected to argue that some of the allegations stem from personal conflicts, not criminal enterprise. They aim to “box in” the hotel video with Ventura — describing it as a private, explosive moment rather than proof of a broader pattern of coercion.

But experts warn this approach could backfire if it comes across as victim-blaming. “Jurors don’t like it when defenses try to paint victims as equally responsible,” said NYC criminal lawyer Jo-Anna Nieves. “The key will be whether the defense can show that Combs never crossed the line into coercion or control.”

Jury Selection Spotlighted Public Bias Against Combs, Revealing Cultural Shift

During voir dire, judges grilled potential jurors on their views of sexual assault and Combs’ public image. Nearly 100 candidates were questioned about whether they could be impartial, given the media coverage and social perception of the hip-hop icon.

Diddy appeared visibly tense at times, even asking for a bathroom break during the proceedings. No high-profile allies have appeared in court, and many of Combs’ former celebrity associates have remained silent — a dynamic some say mirrors how quickly fame distances people from controversy.

Missing Witnesses And Few Celebrity Allies Highlight Fragile Nature Of Fame

One of the few celebrities vocal in Combs’ defense has been Ye (formerly Kanye West), though his support has been undermined by his own recent controversies. Former Bad Boy producer Stevie J has also stood by Combs, calling the lawsuits “bogus.” But neither presence is likely to sway a jury focused on facts, not fandom.

As the trial begins, the question isn’t just about Combs’ guilt or innocence — it’s about how power, image, and reputation survive in the face of serious allegations. And so far, Combs is standing in court with few allies and a lot at stake.

Music Industry Insider Highlights Systemic Abuse Beyond Just One Man

In a sobering addendum to the case, music executive Ty Stiklorius shared her own experience with Combs in a New York Times op-ed. She described being trapped in a locked room on a yacht by one of Combs’ associates — an incident she says is emblematic of a wider industry problem.

Stiklorius warned that this isn’t just about Diddy. It’s about a system that has protected men like him for decades. She called out non-disclosure agreements as tools that silence victims in exchange for careers. “This wasn’t consent. It was survival,” she said.

Her words echo through the courtroom, where Combs’ fate may become a symbol of whether the music industry — and society at large — is finally willing to hold entrenched power accountable.